Join the Conversation at 303-477-5600 or text to 307-200-8222 Monday – Friday from 3 pm – 6 pm MT. https://RushToReason.com Health and Wellness Wednesday with Dr. Scott Faulkner — https://castlerockregenerativehealth.com/ (Guest Host) with Regina Nabrit, a Health & Wellness Contributor, and Nathan Lehman, Spine & Orthopedic Specialist. 🎙️HOUR 1 What Does It Really Mean to Be Healthy—and Are You Settling for Less Than You Were Designed For? On this Health and Wellness Wednesday, Dr. Scott Faulkner steps in for John Rush and challenges listeners to rethink everything they’ve been told about medicine, aging, and personal responsibility. From faith and
SPEAKER 13 :
This is Rush to Reason. You are going to shut your damn yapper and listen for a change because I got you pegged, sweetheart. You want to take the easy way out because you’re scared. And you’re scared because if you try and fail, there’s only you to blame. Let me break this down for you. Life is scary. Get used to it. There are no magical fixes. With your host, John Rush.
SPEAKER 11 :
My advice to you is to do what your parents did! Get a job, Turk! You haven’t made everybody equal. You’ve made them the same and there’s a big difference.
SPEAKER 14 :
Let me tell you why you’re here. You’re here because you know something. What you know you can’t explain, but you feel it. You’ve felt it your entire life. That there’s something wrong with the world. You don’t know what it is, but it’s there. It is this feeling that has brought you to me.
SPEAKER 04 :
Are you crazy? Am I? Or am I so sane that you just blew your mind?
SPEAKER 17 :
It’s Rush to Reason with your host, John Rush, presented by Cub Creek Heating and Air Conditioning.
SPEAKER 04 :
Welcome back, listeners, to Hour 3. Dr. Scott Faulkner with Jeremy Sova and Nathan Lehman, my new provider that joined me in the office. So two hours have burned through so fast.
SPEAKER 10 :
They have. And happy anniversary to Regina and Sean. She was just in the studio, but is going home for her 15-year wedding anniversary. So congratulations, guys.
SPEAKER 04 :
Congratulations. So it’s fun that we’re talking about mitochondria because many of you longtime listeners will remember this name. She was a medical student. Actually, she was pre-med in my office. Her name is Advita Bhatia. And she wanted to become a medical student, become a doctor. And so she has now finished her first year of medical school or is finishing up. And she has something really exciting to share with us. But she’s the one who came up with the mitochondria maximizer.
SPEAKER 10 :
That’s right. She actually helped me craft a cocktail that would power the mitochondria via IV hydration. And I twisted it a little bit, and I called mine the Sova Mitomax. So thank you, Evita. Well done.
SPEAKER 04 :
Yeah. And so, Evita, you’re on the line with several of your friends. So go ahead and introduce your friends, please.
SPEAKER 06 :
Yes. Hello, everyone. Hi, Jeremy. It’s nice to hear from you. You as well. Thank you so much for having us, Dr. Faulkner. And just for our new listeners today, my name is Advita, and I am now a first-year medical student at Rocky Vista University here in Parker. And along with me, we’re all part of the organizing committee for the Women’s Health and Wellness Conference that is being hosted at Rocky Vista’s campus next weekend. So I’ll let them introduce themselves.
SPEAKER 05 :
Hi, everyone. My name is Myrna St. Hilaire. I am a second year medical student at RVU, Rocky Vista University. And I founded the conference last year as a first year medical student, along with some of my friends.
SPEAKER 09 :
Hi, everyone. My name is Jambi Kimani. I am also a first year medical student here at Rocky Vista University. And I’m in a really cool position because I was actually able to attend the conference last year as a participant. And then this year, I’m excited to have the honor of being part of the planning committee.
SPEAKER 08 :
Hello, everyone. I’m June Fang, first-year medical student here at Rocky Vista University, of course. I am the marketing team chair for the Women’s Health and Wellness Conference this year, so it’s been very cool watching the whole conference come into fruition and bring it to the community.
SPEAKER 04 :
Fantastic. Thank you for joining us, ladies. So, Advita, first question is for you. What exactly is this conference?
SPEAKER 06 :
Yeah, so this conference is called Women’s Health and Wellness Conference, and This is our second annual conference, and yes, as we said, it is being hosted and organized by medical students. It is actually the only community-facing medical conference of its kind in Colorado, and it’s completely free to attend. So we’re really trying as medical students to bring medical education and make it more accessible for our community. This year, our central theme is on autoimmune diseases and mental health disorders, two areas that are deeply interconnected and often misunderstood in women’s health. And we chose this theme because both autoimmune conditions and mental health disorders disproportionately affect women, yet they’re frequently underdiagnosed, misdiagnosed, or minimized. But not in our clinic, huh, Davida? Not in our clinic, yes.
SPEAKER 04 :
That’s right.
SPEAKER 06 :
That’s what we’re trying to achieve in basically all clinics around Colorado. So, yeah, because patients often experience these delays in care and have their symptoms attributed to stress, or other non-medical factors which impact outcomes. We’re trying to spread awareness through this conference.
SPEAKER 10 :
Fantastic.
SPEAKER 06 :
That was basically our goal.
SPEAKER 10 :
Good. So how do people find out about it? It sounds like it’s free to attend. Where do they sign up? I guess would be the question.
SPEAKER 04 :
So Myrna, do you have an answer to that?
SPEAKER 05 :
Absolutely. That is a great question. So as I just kind of started talking about knowledge is power is what we believe in. And so this conference is really to empower women and knowledge about their health and how to access health care. You can actually access this online. You can sign up for this and register for this conference through the RVU website, Rocky Vista University. You can look up the upcoming events. If you navigate on that, you can look it up on Google. You’ll be able to find the registration link. Once you get in there, you can register for the conference. And like Adbita said, it’s completely free to make it accessible to the community without having to worry about prices or cost of anything.
SPEAKER 04 :
Oh, we like free. So, Jambi, I got a question for you. What kind of information or sessions can people expect? And I know it’s a woman’s conference. Do you have to be female or can men attend as well?
SPEAKER 09 :
That is a great question. Anyone and everyone is welcome to come. Attendees can expect to hear from engaging and knowledgeable speakers. We have speakers that are coming in from RBU faculty. We have some faculty from CU Anschutz as well that will be covering a wide range of topics in women’s health. Beyond that, at the beginning of the conference, we’ll also be providing access to resources. So we have over 15 community resources that are coming in. to talk about resources that they offer for participants to get involved with. They can ask questions. And really, we’re just hoping that this is a space for participants that encourages open conversation about health and wellness. And of course, we would love all of our male friends to also join us because women’s health is not just for women to know about.
SPEAKER 04 :
Well said. So June, question for you. What kind of impact are you hoping this has on the community?
SPEAKER 08 :
Our goal is really to empower women with knowledge so they can better understand their body’s advocate for themselves in medical settings. I think there’s a lot of information that’s not necessarily out there. An example that I like to share is when I tore my ACL last year, I didn’t know that women were more prone to that kind of injury. And so I think there’s a lot of knowledge that can be shared that can prevent things like Things things along that nature from happening given given the information that we can put out there so along the lines with autumn immune disorders. Many patients with those disorders or mental health conditions face long diagnostic journeys and education to really help shorten that path. i’m hearing from experts that will be available at our conference and others with shared experiences also helps reduce that isolation and builds confidence in navigating the healthcare system.
SPEAKER 04 :
Okay, I like it. So, Myrna, back to you. I understand this isn’t just for the public. There’s also a professional education component?
SPEAKER 05 :
Yes, absolutely. So we are actually offering continuing medical education credits, which is essentially credits for physicians, that we are offering 3.25 credits for the sessions that we have this year. We wanted to ensure that the content was valuable not only for the general public but also for clinicians because part of the Women’s Health and Wellness Conference is bridging the gap between physician, medical students, and also the broader community. We’re going to create a space where everyone can kind of feel like they’re learning together. They can ask the questions without worried about, you know, patient doctor, can I ask this? But more so we are all here to learn in the same space together. So that is one of the things we’re offering this year, which is awesome.
SPEAKER 04 :
Wow. CME as a physician, we’re always looking for CME, continuing medical education credits. So that’s nice. So Jambi, another question for you. You said that you attended last year. What was that like?
SPEAKER 09 :
Yeah, it was great. I actually heard about it from one of my friends who is a student here at RVU. And as a pre-med student, I knew I was coming to RVU, so I was eager at the opportunity to kind of start getting involved. But attending this conference as a student last year was a really cool experience. One of the highlights was the fourth trimester conversation. It was interesting to learn about topics that I feel like are often overlooked or not discussed openly. So it was really great to sit in on all the sessions. I really liked that the afternoon had interactive components. So after the lunch slum, people can get up and participate in our pelvic floor therapy. We’re going to have some mental health sessions. But I think it was a really well-rounded conference last year. So I was definitely eager to be a part of putting it on this year.
SPEAKER 04 :
Fantastic. June, I’m going to go back to you. From a marketing standpoint, how are you getting the word out besides this radio show?
SPEAKER 08 :
Yeah, so we’ve focused a lot on community outreach. Anything from like our local groups or local King Soopers even to like the Colorado Medical Society partnerships, word of mouth all around school. Rocky Vista University social media has places where you can sign up for it as well, Facebook, Instagram. And just to reiterate, it is a free event. We really want to remove as many barriers as possible to make sure women across the community know this is a resource available to them.
SPEAKER 04 :
All right. So, Edvita, closing this out because we’ve got to go to a break here really fast, if somebody is listening and interested, what should they do? Remind us when is it and where is it?
SPEAKER 06 :
Yep. So like Myrna kind of reiterated before, you can find this event if you just look up Rocky Vista University’s upcoming events on any internet browser. It is being hosted on our campus, the Rocky Vista University in Parker. It is Saturday, April 11th, next Saturday from 9 to 3.30. So registration will be open at 9. Then there will be a quick breakfast, some resource tables to help you get access with resources. resources around the community and then we’ll go off to sessions. So yeah, you can find it that way. Also, we have some flyers in Dr. Faulkner’s clinics. If you’re his patient, go find the flyer over there.
SPEAKER 04 :
That’s right. So now that you’re famous, will you sign autographs for people that show up and they say, I want my picture taken with Evita and can I get my autograph?
SPEAKER 08 :
Sure.
SPEAKER 04 :
Okay. And I’m going to hold you four ladies to promise that you’re going to go into regenerative medicine, right?
SPEAKER 07 :
We will definitely be incorporating that on the list.
SPEAKER 04 :
Fantastic. Training the next generation, folks, so that someday I can retire.
SPEAKER 03 :
Hey, Advita, could you elaborate on what the fourth trimester is real quick?
SPEAKER 07 :
Yes, absolutely. The fourth trimester, essentially, I actually would have Jambi elaborate on this.
SPEAKER 09 :
Yeah, so it was essentially a session. We have Dr. Patel, who’s a neonatologist, and she was kind of talking about how there’s a lot of talk up until baby’s born and then not a lot about what happens after. But it’s not just postpartum, it’s kind of in all of the resources and like the years to come after having a baby. The program that she had talked about how they can support moms, resources that are available, and kind of what their home care visits look like. So I think for me it was super insightful because I had no idea what the fourth trimester was, but just kind of shedding light again to kind of the mission with this conference to talk about some of these things that I’m sure many women are experiencing but kind of aren’t talked about.
SPEAKER 03 :
Thank you. My wife, Laura, is in her fourth trimester right now, so I thought it was important.
SPEAKER 06 :
Oh, well, Jeremy, for you, just to kind of add information on that, there is an organization called IANA that we just had a session with at school. And they’re like, you are not alone. It’s essentially for women who just had, you know, a baby and are in postpartum care. So it’s a great resource if you ever want to get connected. And they’ll be at the conference as well.
SPEAKER 04 :
Fantastic. Ladies, thank you so much for doing this. Really, it’s incredible work. So I applaud you. I wish I could be there, but I already have a previous commitment. Maybe, Nathan, you can go to that on that Saturday.
SPEAKER 01 :
With my wife, we were talking about it already.
SPEAKER 04 :
Yeah, that would be fantastic. And people, you can get Vita’s autograph. She promised that. So Rocky Vista, go on their website and attend the conference, please. Great job, ladies. Thank you for having us. You’re welcome. We’ve gone a little bit long. We’re going to take a break, and we’ll be right back. Dr. Scott Faulkner, 560 KLC.
SPEAKER 01 :
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SPEAKER 04 :
Welcome back, listeners, Dr. Scott Faulkner and friends. Thank you, Advita, you and your friends. Go to Rocky Vista website and please attend the conference. I think you would find it well worthwhile. So I’ve been promising that we were going to talk about Clotho for the last two and a half hours. Two and a half months. Yes, two and a half months. So now in the next 30 minutes, I know most people have not heard of Clotho. We teased this a couple of months ago. here it is. Jeremy, what is Clotho? What’s the history behind it? Why are these guys on the radio even talking about this?
SPEAKER 10 :
Right. And I didn’t know what it was either until you invited me to the A4M conference in Vegas. And there was a lot of buzz about it. And then some specific people that were using it in their products. And I’m like, what exactly is this? You know, it sounds like cutting edge stuff, but it was kind of over my head. So I bought a book called The Clotho Effect, and I shared it with you, and it was like 700 pages.
SPEAKER 04 :
Yeah, 660, yeah.
SPEAKER 10 :
And found out pretty quickly that it’s a pretty important thing to understand and test for and track and try to increase or upregulate what we’re calling circulating Clotho. Clotho is with a K, K-L-O-T-H-O, and we’re calling it the Clotho Longevity Protein. So where did that name come from? The protein was named after Clotho, with a C, one of the three fates in Greek mythology, who spins the thread of life. So the name was chosen deliberately to reflect the gene’s apparent role in determining lifespan, healthspan, and biological aging. So it was discovered back in 1997. This gene was identified by Makoto Kuro and colleagues during experiments in genetically modified mice. So the mice unexpectedly developed accelerated aging symptoms, including shorter lifespan and multiple age-related diseases, pathologies. So their investigation revealed the cause was a loss of function mutation in previously unknown gene, which they now called Clotho. So this discovery was big, even though it was 30 years ago, because it showed the mice lacking Clotho aged quickly. But the ones overexpressing or upregulating Clotho lived longer.
SPEAKER 04 :
Twice as long.
SPEAKER 10 :
Twice as long. So it was very apparent the gene was acting as like a systemic suppressor of aging, not for any particular organ system, but kind of across all parts of the body. So that was pretty amazing to see. And from a physiological standpoint, it’s produced in the kidneys mostly with additional expression in the choroid plexus of the brain, the parathyroid glands, and then found in blood, spinal fluid, and urine. And the evolution of looking into this has turned into it being a big forecoming part of regenerative medicine. And we wanted to understand it, unpack it, and see how does it apply to what we’re doing at Castle Rock Regenerative Healthcare. And it basically taught us that it influences system-wide aging processes versus any single organ system. Mm-hmm. So me, as the biohacker, I’m like, well, I want to know what my clotho is, and I found out it wasn’t that easy to find out. That’s right. So I found two companies worldwide, one that I found to be the best choice. It was a Japanese-based company, and ordered the test and tested for it. So now, and that’s in process, but when I get it, I’ll know what my baseline is, and then we can figure out ways to increase that So similar to the biological age testing, you know, say you do the ultra panel and you find out that you’re a 65-year-old in a 40-year-old’s body and what can you do to reverse that age? We’ve talked about that for months. We’ve got the ways to do that. Well, now we know if we upregulate the clotho or find out what’s downregulating it, maybe there’s kidney disease, maybe you’re, you know, a smoker, maybe you’re overweight, maybe you have a 13.4A1C and that’s driving metabolic dysfunction. So the ways to get around increasing it is like we always say, you got to find it out, you got to test for it. If you can’t measure it, you can’t manage it. So basically, what’s the evolution of this protein from 1997 up until now in early 2026? They basically decided that the deficiency causes premature aging in the vascular calcification. So what we talk about heart disease. osteoporosis and cognitive decline. So we were talking about Alzheimer’s and what therapeutic plasma exchange can do to reduce that. So, you know, Clotho effects, you know, the kidneys, the brain, the bones, the heart arteries, all the things that we want to make sure we focus on. So in the animal models, it basically improved their brain function when they found out how to increase the clotho levels. So what they did was they, you know, took clotho and injected it into primates. So they went from mice to primates, and now we’re talking about human trials that are taking place. And they found out that these primates were improving their mental spatial analysis, is what they were focusing on. And they came out of it with profound impact. So they basically said… We need to focus on this particularly and how to get it up in neuroprotection. So they also found it’s an anti-inflammatory antioxidant and protects your cells from oxidative stress. So we’ve talked about psilocinescence as one of the hallmarks of aging previously. Well, here’s another way to make sure that you protect those cells from that stress. And just like we said in NAD+, after 40 years old, your circulating clotho levels begin to decline and reach a greater than 50% reduction in older age. So the lower these levels are, the more disease like arterial stiffness, chronic kidney disease, cognitive decline is going to take place. So we’ve got to find out how do we upregulate this stuff? How do we increase this protein? And then as of, I think, last month, research has moved into active clinical development in several companies to do it and restore it in humans. So a landmark study just recently published in Nature Aging led by Dr. Dania Dabal at University of California, San Francisco. Like I said, post-Clotho injection, they showed a 60% jump in spatial memory tasks in And like we’ve spoken about, there’s a sweet spot in all this stuff. More doesn’t mean better. So they found out where lower doses worked while the higher doses did not. So now several human clinical trials are underway. And it’s very exciting because now we know that this clotho thing is real and we can find out ways to upregulate it. We want to incorporate that into the Castle Rock Regenerative Healthcare memberships and a la carte to make sure we can help upregulate this. And I don’t know how much time we have before the next commercial, but I would love to dive in.
SPEAKER 04 :
About 30 seconds. Okay. We’ll hold on.
SPEAKER 10 :
Yep, let’s hold off on that, and then we’ll talk about how can we upregulate this Clotho protein from all things free to all things operation, Clotho upregulation to the stars and everything in between.
SPEAKER 04 :
Yeah, fantastic. Thank you for that summary. So, yes, we’re going to take a break right now, and when we come back, we’re going to tell you guys how to upregulate your Clotho. So you’re listening to Dr. Scott Faulkner and Friends, 560 KLC. We’ll be right back.
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SPEAKER 04 :
You’re listening to Rush to Reason. Welcome back, listeners. We’re almost done, so you’ve got to listen fast for the next 30 minutes because we’re going to give you the keys to the kingdom, how to increase your clotho, which is that longevity gene. We are so excited as doctors, providers. Yes, this information has been there for almost 30 years.
SPEAKER 10 :
Like everything else, it just stayed under a rock and nobody paid any real attention to it. Kind of like cholesterol and eggs being bad for you. When people say it’s been around, it means nothing until you see you regenerative docs and the A4M people putting it in play.
SPEAKER 04 :
And that’s it. It’s the regenerative crowd, those of us that go to A4M and places like that, that have found this and are telling our patients because you’re not going to hear this in your regular doctor’s clinic. They have no clue. You’ll say clotho, and they’ll go, what? Their eyes will glaze over.
SPEAKER 10 :
Greek goddess of what? What are you talking about that for?
SPEAKER 04 :
Yeah, exactly. So now we’re going to give you the keys to how to increase the clotho.
SPEAKER 10 :
Yes, first you’ve got to find it. So we do have that specific blood test that we talked about that I’ve used personally. It is a spitball in here. I think it’s like a $600 or $700 blood. One-time test, but if you want to find out your clotho, you’re basically passing through the cost to get it done from this Japanese company. And then once you have those levels, you can say, okay, well, this is terrible or this is fine or, wow, my clotho is amazing. Once you find out where it is, then you can basically find out how you want to approach upregulating it because we’re seeing in the mice and in the monkeys that upregulating this S-clotho at any means possible, extends your health span and your lifespan, and it’s very trackable, and there’s no denying that this particular longevity protein across all the organ systems, you want to upregulate it as much as possible.
SPEAKER 04 :
Yeah, and you hit it right before we took the break is that what they found is too much of a good thing didn’t work like they thought. Right.
SPEAKER 10 :
So that’s where the measurement comes in.
SPEAKER 04 :
That’s where the measurement comes in.
SPEAKER 10 :
You find the sweet spot and you track it. Right. So the easiest one that they found, and it should be no surprise to anybody that it’s good for you like everything else, but is exercise. Especially aerobic and cardio exercise is associated with circulating clotho and multiple human observation and innovational studies. So if you need another reason to get off the couch and go to the gym, after we’ve been telling you that exercise is basically number two of all things important after sleep, Um, here’s another reason exercise up regulates that clotho.
SPEAKER 04 :
Yep. And you got to aim for about 150 minutes a week.
SPEAKER 10 :
Yeah. Minimum. I would say anything, you know, 200, 220 is good, but that zone two cardio, here we go. We know it’s great for the heart. Now we know it’s great for upregulating clotho. So God designed this body in a way it all of a sudden seems like all these things that we should be doing are helping in multiple areas with multiple modalities.
SPEAKER 04 :
That’s right.
SPEAKER 10 :
And Clotho is no different. Another one, which we’ve talked about a bunch, is maintain a healthy vitamin D status. And when we say healthy vitamin D, it is not the 30 that your doctor says. Your annual is a good number. It is, in my opinion, between 75 and 90. Because if you go over 100, you could have some calcium issues.
SPEAKER 08 :
Mm-hmm.
SPEAKER 10 :
And anything under 70, you know, you’re starting to get into lower amounts. If you’re north of 55 or 60, you could supplement more. You’re in decent shape. But that 75 to 90 range that we track and look at every three months is important. So the vitamin D is linked to the Clotho expression in deficiency. But also you’ve got to make sure you reduce the phosphate load because high phosphate in your diets and your foods or additives suppress clotho. So limit foods with phosphate additives and avoid unnecessary phosphate supplements. So upregulate the vitamin D, downregulate the phosphate.
SPEAKER 04 :
Yeah, one of the worst things that you can drink is soda with the brown coloring. That is awful for your body. So the Pepsis, the Coca-Colas of the world. Not to mention the amounts of sugar that are in that. Exactly. So you’re just putting nothing but toxins in your body when you’re doing that. And you’re right. You really need to focus on folate-rich foods, the leafy greens, the legumes, citrus. Yep. So keep going.
SPEAKER 10 :
Absolutely. So kidney health basics. Clotho is largely produced in the kidney. So control your blood pressure, manage your blood sugar, stay hydrated, avoid unnecessary, you know, NISAD use, which is what your Advils and your… Ibuprofens or NSAIDs. Ibuprofens, Motrins. So limit those. And again, back to the basics, sleep and circadian rhythm regularity. Poor sleep and chronic stress correlate with worse metabolic inflammatory status. Imagine that. And that’s unfavorable for this Clotho protein. So big shocker. Sleep’s always been number one, and it’s very important for another reason. Yeah, you mentioned the anti-inflammatory diet. Make sure you’re getting your fatty fish, your omega-3s. Minimize ultra-processed foods and added sugars. And get a healthy body composition. So we can talk about these GLP-1s to help you get there and the proteins. But obesity and insulin resistance are associated with lower clotho. So gradual fat loss and improved fitness are going to up your clotho. Don’t smoke. Cigarettes lower clotho. Limit heavy alcohol. That lowers clotho. Also worsens oxidative stress and inflammation. And then here’s one which has always been my Achilles heel, and I continue to work on it, is manage your chronic stress. So mindfulness, you know, breath work, leisurely activity, you know, vacation, because it’s directly linked to inflammation and autonomic balance. And I’ll go back to this vacation that I was just on. I said something along the lines of it’s important how you vacation. And I brought, you know, all my peptides and my longevity meds and, you know, my aminos for my coffee. And, you know, I got exercise in the morning and, you know, breath work at first light. There’s a little more alcohol than I typically do, but it was all-inclusive vacation. I wanted to have a little bit of fun. But outside of that, I realized that my mindfulness and the chronic stress markers on my aura ring were finally coming into play in a good way. And my resilience was going up, you know, from solid strength. from adequate to solid to optimal by about day four. And I really truly did unplug for the first time in several years because I’m always on kind of a guy. But I’m learning that that weakness of managing chronic stress is something that you really got to put the work in for it. You know, it sounds easier than it is, but it is extremely important for your emotional health and your stress markers. So there you go. Chronic stress down-regulates clotho. Big shocker. Yeah.
SPEAKER 03 :
A lot of these things go well together. A good way to manage chronic stress is to get into a regular exercise routine and get out in the sun. There you go. Which helps you absorb your vitamin D and the exercise. You’re also building willpower. If you don’t like the word aerobic exercise… Go out and exercise your willpower. Push yourself to the point where you’re going to break and then push yourself a little bit more. Love it. And then you’ll find that that translates straight over into a work environment, into a career, optimizing things for your family. Push the exercise. Get out in the sun and manage your chronic stress.
SPEAKER 04 :
Yeah, and eat well.
SPEAKER 10 :
But once you get into the habit, you’re going to realize, wow, I really enjoy this. And it’s no longer a willpower need so much as looking forward to the exercise or looking forward to the good meal because your body is going to tell you. And once you come out into this cloud and get off of zero and move into the right healthy lifestyle. you’re going to want to feel like this every single day. I told Dr. Faulkner this morning, like the one thing that was missing from vacation, other than the hyperbaric chamber, was the red light. You know, I got my cold plunge, I got my sauna, I got my exercise in, got the breath work in, got the sunlight. But I really was craving red light because now that I’m in it four or five days a week for a couple of years, my mitochondria is firing so good that even a few days off, I can feel a noticeable difference. And I wanted to like go find the general manager of the resort and be like, you need to get a red light bed for your guests. Like they have at the Bellagio in Vegas. But now I know why, you know, the, you know, the famous longevity folks, you know, Gary Brecka and They’re actually ordering cold plunges and red light beds into the resorts before they go on vacation and pay for those and say, you can keep them, but I want to use them while I’m there. Now, that’s really excessive, but it goes to show how much of an impact that it has in their lifestyle that they don’t even want to go a week without it. Yeah, exactly.
SPEAKER 04 :
And some of the other simple things that you can do is vagus nerve stimulations.
SPEAKER 10 :
Yes. Yep.
SPEAKER 04 :
Absolutely. So you do that.
SPEAKER 10 :
I do. I have, um, a Vegas nerve stimulator and I also use the cryotherapy. So I go on the cold plunge below the, below the brainstem. Um, but I did find out, you know, for me personally, that in addition to those modalities, I have to be very present and focused on kind of shutting things down, you know, and it relates to sleep too. So, you know, phone off a little bit earlier. Um, But I did see the best numbers outside of, you know, me doing like a harmonic egg type meditation when I really got into the vacation and kind of just let things go. So, you know, for you employers out there that are beating your employees to death and limiting their time off. Um, if you want them to be healthy, you know, get them a GLP one and another vacation because the healthier your employees are, the more productive they’re going to be. And they’re going to love that you’re buying into their health and it’s going to help in the big picture because it is very important to get that rest time. That’s exactly right.
SPEAKER 04 :
So what do you do for rest and relaxation, Nathan?
SPEAKER 03 :
Spend time with my family right now. Being with my baby is the best way to just completely reset, feel good, be with my wife.
SPEAKER 10 :
Boost those oxytocin levels.
SPEAKER 03 :
Yeah, yeah. Feeling real family love. That’s a great way to reset. One of my peak times of the day also is when I get exercise in, when I push myself to the point where I broke myself or almost broke myself, and then I recover afterwards, go spend time. That time with my family after a good exercise is much more precious than if I skip the exercise I’ve found because of how it makes me more mentally present in situations truly relax. If I think if I looked at my heart rate after exercise, it comes down to a much more relaxed level versus if I skip the exercise for the day, and was was just, you know, spending time with the family trying to relax, but you know, work is still on my mind, you got to break away from work and go home and exercise for me is how I break away.
SPEAKER 10 :
Yeah, it’s great for several reasons. But recovery is important too. So I’ve always done the overshoot the goal, miss the sweet spot, do too much. But I’m four days on, three days off now in the gym and with the Zone 5. I do the Zone 2 daily. But I found out I actually recover faster, muscles grow faster if you give the body time to kind of bounce back and heal. So those that are like, oh, I’m going to run a 100-mile marathon through the mountains seven days a week, that down regulates clotho first of all and it’s your body needs that recovery not just at sleep but you know to avoid too much strenuous activity and for you hikers out there like get out in god’s country but the data is showing that circulating clotho drops precipitously the higher you go at elevation so the recommendation is to get like a two pound oxygen concentrator for your backpack and have the oxygen breathing in when you’re hiking up 12 13 14 000 feet And those 100-mile runners, it is actually crushing your clotho. So as much as I know you love it, you’re addicted to the run, you get the runner’s high, there is better ways biologically for you to stay healthier. So that’s a bit of a warning for those extreme folks out there. The extreme stuff and the high elevation stuff is actually bad for circulating clotho.
SPEAKER 04 :
Good to know. So we better take a break. We’ve got the last segment. We’re going to talk about statins and other things. Are they good? Are they bad? We talked about this last time. We’ll give people some advice on that. And then we’re going to finish up with Nathan and all the things that you can do for folks since you’re the newest in the clinic. So stick with us. We’ll be right back. 560-KLZ.
SPEAKER 15 :
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SPEAKER 18 :
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SPEAKER 04 :
Back to Rush to Reason. Welcome back, listeners, to 560 KLC, Health and Wellness Wednesdays. For those of you who have been praying, the Lord has answered our prayers. If you look out, it is raining now, so hallelujah for that. So, Jeremy, this is our last segment. We need to hit all the different things that, besides what we’ve talked about, how can we upregulate clotho?
SPEAKER 10 :
Yeah, so that’s been the challenge was looking into ways to do this other than the natural ways that we just discussed. And with the book and then using AI and then looking at some of the current trials that are going on, you’re going to be a little surprised to hear that certain statins, which everybody has been saying statins are bad, they cause diabetes, they cause brain disease, they cause muscle weakness and soreness. A lot of that is true, but it doesn’t mean that if you take the right statin under the right circumstance and under the right regimen, that it’s not a net positive. So I have changed. And so have I. And gone on to, so there’s simvastatin. Zocor, yep. There’s atorvastatin. Lipitor. And fluvastatin. Yeah, old guy. And all the doctors are going to want to put you on basically resuvastatin. Which is Crestor. Which is Crestor. That one in particular does not seem to upregulate circulating clotho, but the previous ones that we just mentioned do. Okay. So what I found out, again, the sweet spot, because I was on enough to give myself some muscle weakness, having some side effects over the years. So I went, you know, to the thinking about cholesterol only and lipids. You know, I basically went to red yeast rice and azetabi, which we’ve talked about before, azetia. But what I’m doing now is I call it kind of a hit and run where I’m only taking the statin three days a week. I’m taking this statin that upregulates Clotho, and I’m finding that my cholesterol and lipid panel numbers are maintaining perfection. Total cholesterol, 102. ApoB, 38. LP, little a, 10. HDL, 67. LDL, I believe it’s like 52. Yeah. And however, my particle sizes are still bad. I got the golf balls, not the beach balls. So, you know, we’re picking away at this, and we’re increasing it over time. So now we’ve made this change in the statin, and I want to track the upregulation of the clotho. So yeah, folks, not all statins are bad, and not all statins are evil, like you’re being told by the, you know, people between the cardiology department, which is going to throw a statin at you as soon as they see cholesterol. The other side of the coin, the never touch a statin whatsoever for any reason it’s bad, sweet spot. Now we’re talking about right statin, right reason, track it, find out what it’s doing for you. So not all statins are bad for all you, you know, functional healthcare folks out there. Um, another means we talked about previously too, cause it also helps with cellular senescence is the combination of the satin nib, which is a leukemia medication and care sit in, look at that. I pronounced it. It took months care sits in, which is a flavonoid called D plus Q. So you put those two things together, similar hit and run. And that upregulates Clotho as well as has other benefits to it, like we talked about in cellular senescence. It helps get the zombie cells out. Don’t like zombie cells. In the new one, and I’m starting to see different manufacturers that are kind of fighting each other to get market share, but Clotho monoclonal antibodies. So those of you during COVID had heard that term, monoclonal antibody. So now these companies are making Clotho antibodies that you can inject similar to what they did with the monkeys to upregulate their Clotho. And I’m going to need help, Doc, but RAS, renin.
SPEAKER 04 :
Renin angiotensin system.
SPEAKER 10 :
Yeah, so blockers. Tell us what that is because those upregulate Clotho.
SPEAKER 04 :
Yeah, so renin angiotensin is the system in your kidneys. And the most famous ones are your ACE inhibitors. So, or ACE receptor blockers as well. So what happens is when you get that system revved up is you get vasoconstriction and it can limit blood flow into the kidneys. And what do we say? Blood flow to the kidneys is important. Healthy kidneys increase clotho.
SPEAKER 10 :
Yep. Absolutely. Because most of the clotho is circulating from the kidneys. Correct. Oh, so that makes a lot of sense. So what about SGL2 inhibitors?
SPEAKER 04 :
Yeah, so there’s several of them on the market. So everybody’s heard of the GLP-1s. So before that was the SGL-2, T2, like Genuvia. It was probably the most famous one. So oftentimes I’ll combo Genuvia with a GLP-1.
SPEAKER 10 :
If you’re trying to lower A1C.
SPEAKER 04 :
A1C and upregulate clotho. Gotcha. Right? So our buddy James, who called in, that’s before we go to insulin, he needs more help. So we would try that combination.
SPEAKER 10 :
Maybe fix it systemically versus having to go all the way to basically insulin shots.
SPEAKER 04 :
Correct. Now, really, the SGLT2s are really designed for diabetics, whereas the GLPs, we use it in non-diabetics. Gotcha. Wouldn’t I don’t use those that class of medicine in non diabetics, but the ones for biohacking like you and I, we don’t have diabetes, right? But I do mine about every 12 days. Right, because my dad died at 45, massive heart attack. My grandmother had Alzheimer’s. So I’m biohacking to mitigate that risk. And I’m also trying to upregulate Clotho. And that’s why I work out every morning on my Carol bike.
SPEAKER 10 :
So that makes sense. And as we get through these clinical trials and we see exactly more data. Correct. Correct. Correct. relatively easily compared to how this would have been 10 years ago. And the last one, which Brian Johnson and myself are using for, uh, different reasons is metformin.
SPEAKER 04 :
Yeah.
SPEAKER 10 :
So I pair rapamycin, which is a rapalog that helps, um, longevity, aging health spans been, been shown, uh, And I pair it with metformin. Yeah.
SPEAKER 04 :
And you have to be careful with the rapamycin. We’ve had that discussion before.
SPEAKER 10 :
Yes. Again, sweet spot. And it took me a year and a half to figure out what mine is. And now I’ve, I’ve talked to him for a few months now, but it is my sweet spots, 10 weeks on five weeks off that no immuno issues whatsoever. Um, so like finding that sweet spot should be its own podcast in and of itself. And thyroid, um,
SPEAKER 04 :
Yeah, so we had a caller who asked about a thyroid issue. And so thyroid is a very complicated organ system in your neck, right? And think of it as the thermostat in your body. So this is a little bit off topic of the clotho. But since a caller asked the question during the break, I thought we would answer it in the last couple of minutes that we have. And that’s why you were a little confused. Sorry for that look. All good, I remember now. Yeah, so the short answer is come in and talk to Nathan. But there’s underactive thyroid and overactive thyroid. And if you have something like Hashimoto’s, which is an autoimmune disorder, then initially you have an overactive thyroid typically because it’s burning out. It’s revving fast like the thermostat turning it up. But then over time, your thyroid can burn out, and now you become hypo or underactive.
SPEAKER 10 :
which is more common in my experience.
SPEAKER 04 :
Correct. So oftentimes we’ll miss somebody in the hyperactive phase or doctors won’t do the autoantibodies to look, do you have an autoimmune disorder? Is this Hashimoto’s? The other thing that I taught Nathan, I think, a couple of weeks ago, is the sweet spot for the TSH, thyroid stimulating hormone, that every doctor checks but they don’t do the full panel, is around 1.0. So there’s a huge study that I showed him, 9,500 patients out of Rotterdam in the UK. And even people who had a quote-unquote normal TSH around four, four and a half, you were at massively increased risk of cardiovascular events than if your TSH was closer to one. Wow. So even though you’re in the quote-unquote normal range, it’s not normal. So we optimize people. We split hairs. So we try to get your TSH to close to 1, and that comes into play, the T4 and the T3. So T4 converts in your body to T3. And, again, T3 is what sets your metabolism. Well, doctors, oftentimes, if they see your TSH is high, they’ll just throw Synthroid or T4 at you, but they forget T4 has to be able to convert to T3.
SPEAKER 02 :
Gotcha.
SPEAKER 04 :
So they’re only treating half the problem. And so if you’re like, I’m still not feeling better, they’ll just keep flogging that horse, man.
SPEAKER 10 :
And guess what? Apparently, according to Gemini, my AI, there’s thyroid protection. Higher serum clotho levels are associated with a lower risk of developing hypothyroidism. And in tumor suppression, clotho acts as a tumor suppressor in the thyroid tissue, inhibiting growth of certain cancer cells in your thyroid. There you go. So how do we close that loop? on time. And stay tuned because next month we are going to break open the microbiome, which is the gut brain barrier connection, for three hours and blow everybody’s mind and change the way that you work your gut.
SPEAKER 04 :
Yes, sir. So it’s been fun. Nathan, thank you for being in the studio with us. We look forward to you next month talking about everything spine and pain. And we’ll see you guys in a month. Scott Faulkner, 560 KLZ.
