Join Dr. Scott and Jeremy Sova as they navigate the fascinating intersections of traditional medicine and innovative treatments. From the neurological benefits of methylene blue and hyperbaric therapies to the nuances of psilocybin in mental health, this episode challenges conventional wisdom. A special focus is placed on the extraordinary anti-aging potentials of rapamycin, revealing insights into how this ancient compound is reshaping our understanding of longevity. The conversation also unfolds into discussions on the potential of psilocybin and ketamine to ease depression and anxiety, providing fresh perspectives on mental health management.
SPEAKER 04 :
This is Rush to Reason.
SPEAKER 06 :
You are going to shut your damn yapper and listen for a change because I got you pegged, sweetheart. You want to take the easy way out because you’re scared. And you’re scared because if you try and fail, there’s only you to blame. Let me break this down for you. Life is scary. Get used to it. There are no magical fixes. With your host, John Rush.
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My advice to you is to do what your parents did! Get a job, sir!
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You haven’t made everybody equal. You’ve made them the same and there’s a big difference.
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Let me tell you why you’re here. You’re here because you know something. What you know you can’t explain, but you feel it. You’ve felt it your entire life. That there’s something wrong with the world. You don’t know what it is, but it’s there. It is this feeling that has brought you to me.
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Are you crazy? Am I? Or am I so sane that you just blew your mind?
SPEAKER 04 :
It’s Rush to Reason with your host, John Rush, presented by Cub Creek Heating and Air Conditioning.
SPEAKER 05 :
Welcome back, listeners. It’s actually Dr. Scott filling in for John on this beautiful Health and Wellness Wednesday in Denver, Colorado, Hour 2. For those of you who missed Hour 1, I’ve been talking to Jeremy Sova, who is a patient-slash-client of ours at the Castle Rock Regenerative Healthcare Center down in Castle Rock. And we are talking about intelligent aging and all the things that Jeremy’s done because he’s on the same journey as most all of us because we’re all getting older. The clock is ticking. Some things we know about, some things we don’t. But before we get back into Jeremy’s story, I wanted to remind folks that. I am now one of the principal investigators for a new medication. I’ve signed a nondisclosure, so I can’t tell you the name of it, but it is actually to treat Alzheimer’s dementia. And it is going to be incredible. The studies that have been out, people who have a mini mental status exam score of, say, 19, they’re getting back up to 30, and 30 is a perfect score. It is given as an IV infusion. It’s typically one infusion every 28 days. The average person needs about six infusions. So if you want to learn more and the next question, and I will just be blunt, no, insurance doesn’t cover this because this is an investigational new drug. and um under the compassionate use so unfortunately insurance doesn’t pay for this but if you have a loved one and you want the methylene blue and you want the hyperbaric that we do at the office but this new medication is insane and how it reverses dementia um I am the only principal investigator that I know of in northern Colorado doing this now. So if you want more information, reach out to my office, 303-663-6990, and I’ll be happy to guide you and see if your loved one is a potential candidate for this. The exclusion is you have to be 56 years or older. So it’s not for younger folks. That’s just the rules they set down for this medication. So pretty exciting stuff. Well, that’s very cool.
SPEAKER 16 :
I heard you mentioned something called methylene blue in there.
SPEAKER 05 :
Yes.
SPEAKER 16 :
There’s a lot of chatter about that. What is it doing?
SPEAKER 05 :
So I had Dr. Fortin on, my neurologist partner, because we’ve created this brain center in the office with the hyperbaric chamber. He does a lot with traumatic brain injuries, dementia, PTSD, things like that. And methylene blue was invented back in the late 1800s as a dye for blue jeans. And who’s the first person who ever decides to test this stuff or use it? I don’t know. But it’s any neurologic condition. It improves the synapses and it’s anti-inflammatory. So at low doses. high doses can start to get you into trouble. And we’re talking 50 milligrams down is a safe dose. You start getting 100 or more, and you can get side effects. But it repairs the synapses in the neurons of your brain. And basically what Dr. Fortin says is if you have a neurologic condition, anybody should be on methylene blue. So Judy, my wife, and I, we started taking methylene blue. The really cool party trick is it turns your pee green. I get blue and yellow make green. But I’ve started giving it to any of my patients who have cognitive impairment neurologic disorders and we’re actually seeing improvement along with the hyperbaric because it’s multi-modality sure but um in a nutshell in layman’s terms without getting too scientific that’s basically the nuts and bolts of how methylene blue works That’s great.
SPEAKER 16 :
It was kind of a loaded question because I’ve been putting it in my coffee now for about six months in the morning. But I did find out since I have close ones to me that are on serotonin, select serotonin reuptake inhibitors or SSRIs.
SPEAKER 05 :
SSRIs, yeah, Prozac, Paxil, Lexapro, those. You could get a serotonin syndrome, but again, when we’re in the safe zone, because I prescribe 15 milligrams, you’re not going to see a serotonin syndrome.
SPEAKER 02 :
Oh, great.
SPEAKER 05 :
Because when you get the higher doses, then you can start getting into trouble. Gotcha. But that opens up a whole other can of worms is should you be on an SSRI or not? And I told you before we went on air that I have a friend of mine, Sam Peterson, who owns my spa Denver on Frequently. And I did not know this. Sam taught me that in the studies, they did a head-to-head study, Prozac versus Saffron. And Saffron is actually more effective as an antidepressant than Prozac. It’s incredible.
SPEAKER 16 :
A flower over a drug. Imagine that.
SPEAKER 05 :
We now know that depression has nothing to do with serotonin. Literally. And I just learned that through the A4M conference two weeks ago. Wow. So we have been throwing pills at people right and left, making them zombies. Because what I’ve noticed, and back when I was a young doc in the early 2000s, is, oh, you have depression or anxiety, you need an SSRI. And So my patients, they would say, well, I’m not depressed, but I’m not happy. And the word that every one of them would say is I feel like a zombie. I’m just kind of numb in between. I don’t feel the highs. I don’t feel the lows. I can’t stand this. So now our job is to try and peel people away and off these SSRIs. And I guess we should just go there because we had talked about, um, psilocybin, which I don’t have a lot of experience with. So I send people over to Sam because he does a lot more with the psilocybin. For those who don’t know what psilocybin is, it’s magic mushrooms, right?
SPEAKER 16 :
So the primary drug in mushrooms.
SPEAKER 05 :
Yeah. So when you were in college and you were tripping and you saw cool colors, um, it was a psilocybin high. We’re not trying to get you high, um, necessarily. We’re actually trying to rewire your brain. That’s correct. And so if you want to take that and run with it, go for it.
SPEAKER 16 :
Sure. So being in the cannabis industry for several years, you would hear about medical benefits potentially with both THC and psilocybin, which was kind of the next wave. Didn’t pay a whole lot of attention to it. And I had used it recreationally in college many, many years ago. And probably in more macro doses than micro doses, and in some cases not enjoyable at all. But as it’s evolved, and I’ll basically plug Dr. Andrew Huberman out of Stanford, he spent, you can look it up, he’s got a podcast episode on psilocybin, I think it’s about two hours in length, and he breaks down, and it’s all backed by studies and proof, but he breaks down that somebody that is on an SSRI or is clinically depressed or has severe anxiety, can take two macro doses about 10 days apart in a macro dose, probably in the 250 to 300 milligrams per. The key is you have to be blindfolded. That’s like the secret recipe is you cannot take the blindfold off. It’s a six-hour journey times two, 10 days apart. And you lay the patient down blindfolded in a safe space, safe room with a babysitter that’s not on psilocybin or any other substance, so to speak. And you start with real slow classical type music, some Mozart, some Bach, some Beethoven. And then like kind of hour two or three, you start to kind of take things up and to a point that you kind of peak or climax at a lot of heavy percussion and, you know, medley sounds really intense. And then you kind of take it down into what I call like the Enya type spa music, real relaxing. And in that six hour journey, you know, it’s kind of part one. Then you wait 10 days and you do the same thing a second time. And the research is showing and the results are showing and the patients are telling their stories that it literally rewired their prefrontal cortex permanently, you know, for the rest of their lives correctly. So they no longer have these anxiety or depression issues. So it’s not like you’re taking, you know, mushrooms every day to try to manage it, you know. And again, you know, recreational use of certain things is a kind of a different topic today. But you can really fix the brain, you know, versus being on these what I call these SSRIs or poisons.
SPEAKER 05 :
Yes.
SPEAKER 16 :
You know, and they’re on them. I mean, I have loved ones that have been on for decades. All right. And they’re afraid to kind of step outside the box or wean down. And there’s you can’t really pick up the phone and ask your primary care physician about it. Right. You know, they’re probably going to fire you as a patient. So it’s an emerging space. I think it’s a very interesting one. And then you start to see the introduction of what they’re calling really low-dose ketamine. You’ve got different isomers.
SPEAKER 05 :
So let’s hold on to low-dose ketamine. We’ll pick that up. We’re going to have to go to a break and then take the segue for low-dose ketamine when we come back. Sounds good. So you’re listening to Dr. Scott filling in. John Rush, 560 KLZ. We’ll be right back.
SPEAKER 10 :
Al Smith from Golden Eagle Financial and the show you love, Retirement Unpacked, is here with me. How are you today, Al? I’m doing great. How are you, TJ? I’m doing great as well. I have a couple questions for you.
SPEAKER 19 :
As a financial advisor, do you also do taxes? No, I don’t prepare my clients’ taxes. I do, however, spend a lot of time talking to them about taxes. To use a sports analogy, tax preparation is like doing a recap of the game. What I do is more like creating a game plan and then following up over time to see how it’s working.
SPEAKER 10 :
And how much are taxes a part of that game plan that you create?
SPEAKER 19 :
Well, with so many different taxes we’re faced with, it becomes an important thing to take into consideration. It’s not how much income you have, but how much you get to keep. In addition to federal and state income taxes, there’s property taxes, state and local sales tax, and fees. And they all play a part in shrinking our income.
SPEAKER 10 :
What about people who already have really healthy balances in 401ks, IRAs? Won’t they be facing significant taxes as they draw income from those accounts?
SPEAKER 19 :
Well, it depends. Everybody’s situation’s a little bit different. There’s no one size that fits all when it comes to tax planning. But often when I work with people, we’ll create a strategy where we will convert traditional IRAs to Roth over time. And that not only reduces taxes in the future, but it will also lower the tax they’ll be paying on their Social Security.
SPEAKER 10 :
Is that kind of strategy really only for the wealthy?
SPEAKER 19 :
Not at all. Many of my clients who have modest IRAs have chosen to convert to Roth over time. They enjoy the freedom of having a tax-free nest egg that they can access on their own timeline rather than an RMD schedule.
SPEAKER 10 :
Well, that is excellent. And how can people reach you if they want to learn about their own taxation in retirement?
SPEAKER 19 :
You can reach me through KLZ or contact my office at 303-744-1128. And when you call, I’ll provide you with a summary of all the tax changes for 2025.
SPEAKER 10 :
You heard it here, folks. Good things from Golden Eagle Financial and Al Smith. Again, you can reach them at 303-744-1128 or just find them on the advertisers page at klzradio.com.
SPEAKER 17 :
Investment advisory services offered through Brookstone Capital Management, LLC. A registered investment advisor. Putting reason into your afternoon drive, this is John Rush. It’s actually Dr. Scott filling in for John Rush on this beautiful Wednesday. John had a thing with a grandchild, so…
SPEAKER 05 :
He said, hey, can you fill in? I said, absolutely. So here I am, and I brought Jeremy Sova, one of my patients slash clients, with me because his story is classic, and I thought the audience could learn a lot from somebody who’s not myself because I could just spill out medical stuff all day long, and your eyes would glaze over, and you’re like, who is this guy? And I’m tired of listening to him. But when you hear it from somebody who’s a layperson, businessman, very successful, and But all the things that you’ve gone through, I think it will resonate more with the listening audience. So we had been talking about pharmaceuticals, and we’re going to go back to rapamycin. There’s a couple of things I want to talk about, especially in hour two, because people are driving in their car. People are hopping on, hopping off, not sure what we talked about 15 minutes ago. So we’ll come back to that topic later. But we were talking about low-dose ketamine, and you were going to take that segue and talk about ketamine.
SPEAKER 16 :
Yeah, that’s great. So I’m sure there’s multiple uses for both psilocybin and ketamine in what we call the anxiety and depression space. But my research and people that I’ve spoken to kind of shows that, you know, the fixing the prefrontal cortex for what we call true depression, you know, is really psilocybin specialty. But a lot of folks aren’t necessarily depressed, but they’re very anxious, right? Especially now.
SPEAKER 05 :
It’s huge.
SPEAKER 16 :
Yeah. And the more gadgets we get and the more robots and the harder life gets, you know, anxiety just continues to climb, climb, climb. So what I’ve found with people that I know and people that I’ve read about is that really low doses of ketamine. Let me back up. Ketamine has a couple of isomers. There’s an R isomer and there’s an S isomer. The R isomer is more of what I call a calming for the body. You know, when the S isomer is a little more mind oriented, if you will. So for the purposes of this discussion, talking about anxiety, we’ll focus on the R isomer. But you can take, depending on your body weight, somewhere between 15 and 45 milligrams daily. Orally, you notice a trochee dissolves into your tongue. And within like five or ten minutes, you have this overwhelming tidal wave of calmness that quells any anxiety that you can possibly muster up. And it lasts for about a four-hour period. And if you take it kind of midday, it doesn’t affect your sleep quality. And I found it to be, obviously it’s a disassociative. They’re using them for other things like EMTs, using them for car accidents and broken bones. Take the brain away from the injury temporarily while you can repair it. But from an anxiety perspective, I had no idea. You know, you hear about ketamine here. It’s a horse tranquilizer and people are using it recreationally and going into these K holes. And, you know, unfortunately, God, you know, God forbid, like a Matthew Perry situation where he was being treated for it. And then he also got some more of it on his own and ended up going to a K hole in his hot tub and drowned. So you’d be very careful. But if you’re under doctor supervision, right, and you’re only getting enough, you know, that you need and you’re getting it periodically the correct way. I think it has incredible benefits.
SPEAKER 05 :
That’s exactly right. We’ve seen so many lives changed and getting off of these toxic drugs that Big Pharma wants you to be hooked on for the rest of your lives. It’s truly… amazing what these things can do and again your regular doctor doesn’t know about this he’ll hear the word ketamine is like that’s an anesthetic or that’s what matthew perry overdose with no why you can’t have this go away right and that’s why i’ve teamed up with uh sam peterson there at mind spot denver because i do what i do very well but there’s things that i don’t want to touch And as we were talking during the break, I had looked at ketamine since we do IV fluids, IV infusions, that I thought, okay, well, this could definitely help because I have so many friends that are veterans, have PTSD, traumatic brain injuries, the whole nine yards. I thought this ketamine can definitely help them. But the more I learned about that journey and you can hurt somebody very, very badly and very quickly if you do not know what you’re doing. Sure. So I said, if I can’t do it well, I’m not going to do it all. So I’ve opted to team with Sam and the guys at MindSpot Denver and say, that’s your field. That’s what you do all day, every day. You do it very, very well. And you take insurance, whereas I don’t. And so, but a low-dose ketamine or even like a low-dose naltrexone, right, for autoimmune disorders and chronic pain so I don’t have to give you a pill of OxyContin or morphine or something like that. We have so many cool alternatives. That reminds me, I wanted to talk to you about CBD and CBG for pain since you were in that space. But we have to go back, remember, and we were going to talk about rapamycin.
SPEAKER 16 :
That’s right.
SPEAKER 05 :
So we have to finish that thought first before we go into some of these alternatives for pain. And since you’re an expert, you were in the field, I thought who better to ask? Sounds great. So let’s talk about the rapamycin. Back to that, those who missed it in the first hour.
SPEAKER 16 :
So rapamycin, call it a drug that’s been around for a long time for organ transplant, making sure an organ in a patient takes appropriately. Turns out it was originally founded in Easter Island, middle of the ocean, volcanic island southwest of the Peru-Chile area. And all kinds of locals were living over 100 in a number that wasn’t seen in other populations throughout the world. And they found out that there was Rapamui is the name of the volcano, which rapamycin came from. So they basically were drinking the groundwater from the volcano and they were living longer. So now we’ve learned that you can harness the power of rapamycin in the correct dosages. And it’s very important that you titrate up very slowly over time. Um, unlike, you know, Brian Johnson from Netflix, the don’t die guy. Um, you want to start very slow, take a break, one milligram month off, two milligram month off and work up. My sweet spot for me is about 6.6 milligrams now. And it’s taken me almost two years to get here very slowly titrating up. Um, and you’re attacking what they call mTOR C1, but you’re not overdoing it and touching mTOR C2. So mTOR C1 will help you anti-age, reverse age, improve health span. mTOR C2 will actually accelerate your aging. You’ll start to get side effects like mouth sores and skin issues. So under the right doctor’s supervision that writes you the script and can monitor you over time, You can figure out what the correct dosage is, but rapamycin is probably the number one most important anti-aging pharmaceutical on the planet from what I can tell.
SPEAKER 05 :
And how does that tie in with metformin?
SPEAKER 16 :
Great question. So in some cases, if people are sensitive to hyperglycemia, pre-diabetic, and they’re not using a monitor to check their blood sugar levels, if they dive into rapamycin either too soon, it’s possible that it can increase your chances of hyperglycemia. So what we found is if you pair the rapamycin with 500 or 1,000 milligrams of metformin daily, and we could talk about metformin for a But those two things together prevent what we’re seeing as the one potential side effect that’s negative with the rapamycin use at the right titrated levels.
SPEAKER 05 :
Yeah, that’s exactly right. And as we talked about earlier, it’s all insulin resistance that’s leading our cells to be damaged, long-term aging, Alzheimer’s, heart attacks, strokes. So anything that you can do to prevent that is good. I try to get a lot of people off their metformin and on a GLP-1. But in a case like this, metformin is actually beneficial for you. Correct.
SPEAKER 16 :
I take both the metformin and the GLP-1.
SPEAKER 05 :
Yep. We have a caller, Ben in Evergreen. He wants to talk about inflammatory markers. So let’s take his call and see what Ben has to say. Ben, you’re on with Dr. Scott and Jeremy.
SPEAKER 07 :
Yeah, doctor. This is for either one of you guys. I have asthma. And how often do you see, you know, like a pancreatic insufficiency that’s messing with blood sugar? I have a number of food allergies, but if I eat well, it generally goes away. And with the thing like Dr. Hyman’s got, functional labs or whatever, can they find these inflammatory markers for respiratory problems like asthma?
SPEAKER 05 :
Well, the problem with most inflammatory markers is they’re not totally specific, especially for asthma. Like if you had rheumatoid arthritis, we could do a rheumatoid factor, and that’s more specific. If you had something like lupus, we can do an ANA, and there’s a certain pattern double-stranded DNA that is more specific for lupus. But in asthma, it’s just the fact that you have asthma, you have inflammation, right? You’ve had it for years. We know this for a fact. If you’re having a flare, and I did something called a C-reactive protein or CRP, then your markers will be elevated. But the fact is you have asthma, you have inflammation. So you should be doing everything in your power to decrease the inflammatory with or without asthma. You should be doing everything. So the glutathiones of the world. It’s wonderful as an anti-inflammatory. Asthmatics, you have to stay away from NSAIDs and aspirin, right? I’m sure you’ve been told that.
SPEAKER 07 :
Well, I’ve got my doctor recommends an aspirin a day, but I’ve been I take walnuts, fish oil.
SPEAKER 05 :
Yep, omega-3 fish oil.
SPEAKER 07 :
There’s plant sterols. Okay, yes. I think that’s more for cholesterol. But those seem to be working pretty well. But like you said, if you don’t measure it, how do you manage it?
SPEAKER 05 :
Well, that’s it. You can have more than one thing going on.
SPEAKER 07 :
Right? Yeah. Yeah, but I like that statement. That is really good. Yeah, Jeremy’s a smart guy.
SPEAKER 16 :
And as a patient, the first thing I would do is I would ask, I would obviously get the Hyman labs done, but I would ask my doctor to test me for all the inflammatory markers in my blood that he possibly could. you know, the SED rate test, the C-reactive protein, and you’re going to start to whittle things down. And you might find out that, you know, simple, you know, umbilical cord stem cell injections every six months could, you know, clean the lungs up, you know, but you really got to figure out which inflammatory markers are elevated and for which reasons. Yep.
SPEAKER 05 :
And back to your question about the pancreas is we do see that occasionally where you have pancreatic insufficiency as well. My down and dirty is I just give people pancreatic enzymes with a few meals. And if suddenly your stools get better, you have no abdominal pain, you have pancreatic insufficiency. I don’t have to get a ton of tests, expensive tests. If the treatment helps, then you’re done.
SPEAKER 16 :
And if you do the function health test, you’ll get the, is it pronase and kinase? You’ll get all the different pancreatic enzyme markers included. It’s one of the organs that they focus on. And if something’s out of whack, it’d be a good place to start digging. Yeah.
SPEAKER 07 :
I’ve taken this supplement before called QBC. I think it’s by now. And when I was doing that kind of hot and heavy, it really managed. It’s got quercetin, vitamin C, and bromelain. And it seemed like it hit the sweet spot.
SPEAKER 08 :
Yeah.
SPEAKER 07 :
But I think I could use some more labs. And then as far as the pancreas goes, I’ve seen some stuff online where they go, hey, your problem, there’s a… what you call, what do I want to say, a parasite or a bacteria in your pancreas, and it’s not blood sugar is what they say. And I’m thinking, that sounds too easy. Where are you guys at with that?
SPEAKER 05 :
Yeah, I mean, as a guy who’s practiced internal medicine and critical care for 29 years, if you had an infection, a bacteria in your pancreas, you’d be in the ICU and I’d be putting a drain in your abscess. So no, you don’t have bacteria in your pancreas.
SPEAKER 07 :
Okay. So we can kind of rule that out.
SPEAKER 05 :
Yes, sir.
SPEAKER 07 :
But I’m going to get with my doctor. And can you do that, these tests? Yes. If you’re on Medicare, there’s a lot of arm wrestling to get them done. You can’t.
SPEAKER 05 :
But you have to – most of these things you are going to probably pay out of pocket because Medicare doesn’t like to pay for things other than basic labs. They will fight your doctor tooth and nail. He has to have specific diagnosis codes, ICD-10 codes. But if you have a creative doctor who will work with you, he can get most of these things paid for. But that’s one of the problems that we run into. And that’s why I just stopped taking insurance. It’s like you’re going to pay or you’re not. You have to make a decision. And so. Like on the pancreas, that’s why I say just try the pancreatic enzymes. It’s fairly inexpensive because when you start tacking on all these biomarkers, these labs, and the price tag can go up. Well, a lot of the patients are on a fixed income or they don’t have that much disposable income. So we have to find creative ways to either treat you to see if it worked and get insurance to pay for it, or we get very creative. And most doctors don’t have the time to get really creative with their ICD-10 codes so that all these different biomarkers are covered.
SPEAKER 16 :
Yeah, my recommendation as a patient is, you know, if you choose to do the function health, I think that’s the best one on the market today. That’s to say there isn’t some competition popping up. It’s 500 bucks, 42 bucks a month. You have to pay one. So $500 for the whole year. And it gives you over a hundred of these biomarkers. So you get the results after three weeks. And if you see some stuff that’s out of range, take it to your doctor. He doesn’t need to order labs. You already have them. Like say, Hey, look, this is off. What can we do about it? That way it takes the pressure off of him, you know, to a certain degree. And if, um, if they’re not willing to work with you, I would suggest getting another doctor.
SPEAKER 07 :
And if I didn’t go that functional health way, which sounds good. But looking at options, if I had to pay out of pocket with some of these other labs, would I get about the same amount of money?
SPEAKER 05 :
No, not even close. More? Oh, a lot more. Because if you just go to a lab, if your doctor just writes a script or you get somebody to write a script and you go into, say, a Quest or a LabCorp, you’re talking thousands of dollars. So, like, I have sat down with the representative from Quest, and I beat them up over price. So things that might cost you $800, in my office it’s $300. But if you just walk into a lab and say, I’m going to pay cash, they are going to rape you. Wow.
SPEAKER 07 :
Yes. Well, I think part of my action plan is get some more of the pancreatic enzymes and maybe try some of that glutathione. Is that an over-the-counter?
SPEAKER 05 :
Well, you can take the precursor called NAC, N-acetylcysteine. Yes. But I’m the type of person, if I want NAC to turn to glutathione, then I just take glutathione. Right.
SPEAKER 16 :
And yes, you can purchase it over-the-counter on Amazon. You don’t need a prescription to get either of those two things. Yeah.
SPEAKER 05 :
Good to know. Well, thanks for the call, Ben. We have to go to a break. We’re a little bit long, so appreciate the call. You’re listening to Dr. Scott and Jeremy Sova filling in for John Rush, and we’ll be right back.
SPEAKER 10 :
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SPEAKER 07 :
Now back to Rush to Reason on KLZ 560.
SPEAKER 05 :
Welcome back, listeners. This is Dr. Scott Filani for John Rush. If you want to join us like Ben did, give us a call at 303-477-5600. If you want to reach me at my office there at Castle Rock Regenerative Healthcare down in Castle Rock, our number is 303-663-6990. Or you can reach us at castlerockregenerativehealth.com. Or again, you can go to John Rush’s website, Rush to Reason. And since I’m one of the sponsors, there’s a link there to get a hold of us. And for those of you who are driving and you’re like, I can’t remember all this stuff, I can’t write it down, this will be on Rush to Reason’s website posted, the podcast, later this evening. So if you need to go back because you missed something or you want to give it to a loved one, especially talking about the medication for Alzheimer’s, again, I’ll give you that information. I am a professional. He’s an investigator for a new medication that has been approved to treat Alzheimer’s dementia. Whether you have Parkinson’s or not, your primary diagnosis can be Alzheimer’s, and a lot of folks who have Parkinson’s have Alzheimer’s as well. No insurance does not cover it. It is an IV infusion, takes about an hour, and the average person does about six treatments, 28 days or thereabouts apart. And the beautiful thing is right now there’s no side effects to this medication. But that’s why they have provisional investigators like myself to get more data, more patients, to make sure it’s truly safe. Right now, there’s been thousands of patients who have not had any issues at all, but it will be a game changer. Unfortunately, insurance doesn’t cover it, but if you have a loved one who’s suffering from this horrible condition, whether or not you can come down and do the hyperbaric chamber, which is one of the things we recommend, the methylene blues, another, the GLP-1s, Jeremy and I were talking earlier about the weight loss medications under the family of GLP-1s. Those of you who missed it in hour one, the GLPs are the semaglutides, terazeptides, and now the latest and greatest is redatrutide. Those medications are showing that it can stave off Alzheimer’s dementia. We now know for a fact that Alzheimer’s is type 3 diabetes. That’s what we’re calling it. It has everything to do with insulin resistance. And so we’re seeing some of those beta amyloid plaques and tau protein actually melt away from people’s brains. So I’m no longer saying, oh, unfortunately, you need this just to lose a little weight and then to come off. There’s actually good reasons to be on these things long term. That’s why I like them a little better than the metformin. But as we discussed with the use of rapamycin, metformin is not a bad thing. And this also segues away into another thing I want to talk about is that true insulin resistance. Because you don’t know whether you have insulin resistance or not. Again, your standard blood panel that you get from your doctor won’t really show this unless, say, you go in there and your blood sugar is 120. And he goes, oh, that’s a little high. We should monitor that. No, you have a problem. I talked to a patient a couple of days ago, and this is exactly what happened to her, is her blood sugar was a little high. Her A1C started at 5.7 and started to creep up, and now it’s 6.5, which is the diagnosis of diabetes. But she was telling her doctor three years ago, hey, should we be concerned? Hey, should we be concerned? The doctor was like, oh, no, you’re in the normal range. You’re perfectly fine. Well, we know what’s coming down the pike. You’re going to have problems. And this insulin resistance is leading to all sorts of bad things down the road, the heart attacks, the strokes, the Alzheimer’s, dementia. So we jumped on it. We got her on a GLP medication. Now her A1C is coming down. She’s feeling better, and we’re going to stave off a lot of these horrible conditions. But one of the things that you can do for yourself without permission from your doctor is you can go online to Stelo, S-T-E-L-O. Stelo is a continuous glucose monitor, or CGM. And I tell my patients, just type it in. It’s made by Dexcom. I don’t have stock. I don’t have any money in Dexcom or Stello. But it puts you in the driver’s seat. So a lot of things that I try to do is empower my patients to do things for themselves, learn for themselves, just like Jeremy. He didn’t need my help. The guy is super smart on all these things. But if you put one of these continuous glucose monitors on, and pair it with your smartphone, is you will see in real time what your blood sugar is doing. And it will be an eye-opener. You will see what kind of foods that you eat impact your blood sugar. So I was just talking to my son-in-law last night, and he had worn one. He’s a baker down at Colorado Springs at the French Bakery. and certain of their pastries you eat one of them and man your sugar goes to 130 and it’s not as much the spike it’s how long does your sugar stay up known as the area under the curve the higher the spike the slower it comes down the more insulin resistance you have And you’re going to see exactly what kind of foods messes with you. And so knowledge is power, right? So if you say, okay, well, if I had a donut and my sugar spiked to 160 and it stayed up for two hours, okay. I think that’s kind of bad. Now you’re going to avoid the donut shop. Sorry, Dunkin’ Donuts owners. But you’re going to make a healthier choice or you’re going to say, no, I don’t need that. So now suddenly you’re in the driver’s seat and you’re empowered. So I throw that out there. Again, it’s called Stello. There might be others. That’s the one that I recommend my patients use. It’s 99 bucks and there comes two monitors in the box. So you and your spouse or a loved one can do it together and make a contest out of it. Say, hey, my sugar is better than yours. And I don’t know, the winner gets a prize or something like that. But something that you can do for yourselves. And the other thing is start getting some aerobic exercise mixed with the weights, weight training. Again, we talked to the GLP-1s in the first segment. Regardless of whether you’re on one of these medications or not, you do need to start getting some exercise. What I have done for myself is I purchased something called a Carol bike, C-A-R-O-L, like Carol Burnett. The crazy thing about the Carroll bike is it kind of looks like a Peloton, but it increases your VO2 max. And what is VO2 max? It’s your oxygen consumption and how well your body, your cells, are utilizing oxygen, the fuel. Well, you can increase your VO2 max like crazy in a 10 minute workout. That’s right. I said 10 minutes. So we’re on your Peloton. You have to sit there for 45 minutes to an hour and you’re racing against a whole bunch of people. I don’t know about you, but I don’t have that kind of time. So the Carol bike will give you the same workout and increase your VO2 max better than anything else out there in 10 minutes. So that’s a little aerobic tidbit that I can give to you, especially in the colder winter months here in Colorado. So something you can do for yourself and then get some weights. Start doing a little weight training. Put some lean muscle mass on your body and it will pay dividends. So we went a little long in the last segment. We’re going to take a break now. You’re listening to Dr. Scott filling in for John Rush, and we’ll be right back.
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SPEAKER 05 :
We don’t yell at you. We inform you. Now, back to Rush to Reason. Dr. Scott Faulkner, informing you on this Health and Wellness Wednesday. And we were just joined in the studio by my good friend, John Flouting, owner, you and your brothers at Revitalize there in Littleton. Like-minded folks. Yes, absolutely. So you had to battle traffic getting over here, but I’m glad to see the whites of your eyes. Nice to meet you, John. Yeah, you too. Yeah. So this last segment, before we go to the top of the hour, Jeremy, we were talking about your journey into first batteries and recycling, then the cannabinoids marijuana, right, in Colorado. And so that brought up a question in my mind because I don’t like prescribing narcotics and a lot of the typical pain medicines for my patients. Sure. And so I started telling them to get CBD, CBG. So you just started rattling stuff off during the break. So I want you to inform the audience, is CBD, CBG good? Is it bad? Is it habit forming? Just run with it.
SPEAKER 16 :
Sure. So the body has an endocannabinoid system, right? You hear about the endocrine system and the nervous system. No one ever talks about the endocannabinoid system. The brain synapses talk to cannabinoids in a way that can help your body under certain circumstances. And to your point, it’s a Schedule I narcotic still federally, so it’s taboo to talk about. Unless you’re in Israel in front of a bunch of doctors, it’s hard to really drill down. But what I learned in my seven years in the industry is that under the right circumstances and for the right reasons medicinally, all the cannabinoids can be helpful. You start with THC, which is the one everyone knows is the psychoactive effects in marijuana that quote-unquote gets you high. There’s a lot of things that that can do that can help you in lower doses. I don’t recommend inhaling it or combusting the plant matter or smoking it, if you will. You know, topicals, edibles, tinctures, drinks. And in very low doses, unfortunately, they make 10 milligram doses. For most people, that’s too much. They should make one or two because it’s pretty powerful. high, if you will. But the key is, is the plant as designed similar to the saffron we were talking about earlier, the plant is meant to be used in all of its component parts together. So you start to strip off THC and you make like a distillate that’s 95% THC. Well, you’ve gotten rid of a lot of the medicinal benefits from the plant. Same with CBD, CBG, and CBN, right? You break off the CBD in a lab. You break off the CBG, the CBN. CBD and CBG have a lot of anti-inflammatory properties, like similar to NYSADS without the side effects and the pharmaceutical uses. And CBN is the one for sleep. You know, it can cause a little bit of drowsiness if you’re not, you know, used to it, but using the plant together when and if possible, and there’s a few places in Colorado that can do this. Like for instance, I’ll throw a plug to, you know, Mary Jane’s Medicinals down in Telluride. She makes a topical that is whole plant infused. Now it it smells pretty funky, right? People are going to think that you’re, yeah, but you know, you put it on the skin and you’re getting all the benefits of the plant as religious as God intended or as earth intended versus just stripping off, you know, some of those endocannabinoids or those cannabinoids separately and So I don’t want to say that if you just get a CBD tincture or a CBN or CBG, it’s not going to have some benefit. But in my experience, I found what they call the entourage effect is all those cannabinoids working together in the plant as one from a medicinal perspective. Recreationally, I can talk for days on this. And what different combinations, you know, can do for you. But that’s probably adding more complication than you expected. But that’s pretty much what I’ve learned.
SPEAKER 05 :
Is that a good place to start, CBD, CBG? And if you get relief, then, hey, you’re good or –
SPEAKER 16 :
I would say so. Like, for instance, I have back issues. We’ll talk a little bit more about them later. But I get weekly cupping and I do bring a topical in that has all the cannabinoids mixed together in. And I found that much more beneficial than if you go to a spa for a massage and you pay that extra 40 bucks for their CBD add-on. Um, I think a lot of the stuff out there is potentially snake oily, you know, so you really got to know the source. You got to know, you know, what’s in it, the profile, how it came to, was it marijuana derived, hemp derived? There’s, there’s a lot to it. Um, but what I’ve, what I’ve learned overall is that, um, the, the more cannabinoids that are still intact and have not been scrubbed out by machines, the better the medical benefits seem to be, if that makes any sense. Hmm.
SPEAKER 03 :
Well, I was just going to say, you know, I was reading some studies also where the soil base to where it comes from makes a big difference. Why Colorado is a good place for it to be grown and extracted.
SPEAKER 16 :
Sure. Yeah, I mean, obviously, the uptake. Getting hold on it, yeah. The right nutrients.
SPEAKER 05 :
Okay, so I’m going to go out there on a limb because I don’t have a dog in this fight, right? Other than my patients are in pain, and I want to give them things like the low-dose naltrexone. I don’t want to give them narcotics. I do recommend CBD, CBG, but I’m not an expert in that field. So go ahead and plug to our listeners some of these places. Since you were in the space for seven years, you did well. What are some of the places that are not snake oil that you would say yes if – and Telluride is a long ways away, by the way. Sure, sure, sure. So my patients are not going to want to go up there. Or if they could order online, I guess that’s an option.
SPEAKER 16 :
Yeah, I can narrow it down, generally speaking, to make it easy. If it’s licensed by the Marijuana Enforcement Division of Colorado, if it’s a licensed dispensary, your chances of getting something that has a lot more efficacy in it is greater than you going to, say, Walmart and buying a jar of CBD off of their shelves. The more commercialized it is, the chances are more of the medicinal benefits have been stripped away. So if you’re looking for CBG, CBD, CBN, a combination thereof, with or without THC, I would start at your local dispensary and just speak to the bud tenders because they know this stuff. Ironically, they can be stereotyped a certain way, but ironically, they’re around these plants and in these labs and with these growers. constantly, right? So they really have the inside scoop of what’s going on. There’s certain, for instance, Rick Simpson oil, very, very potent, high THC. One small little pellet will keep you high for days, but they’re finding that it causes apoptosis in cancer cells. So if you want to numb yourself out for three months and take your stage four cancer down to stage two as a part of other immunotherapy treatments, those are conversations that blood tenders are actually having with cancer patients. Which is hard to believe. So I would say if you’re in the state of Colorado, you’re listening, I would start at the dispensary and ask the bud tender. And they’re mostly going to be honest, like we don’t carry it, but this other place does, you know, because certain suppliers have certain relationships with certain stores. So it can get a little complicated, but that’s where I’d start.
SPEAKER 05 :
Okay. So like my uncle, most people know the story of my uncle who had Lou Gehrig’s disease. And that’s how I got into stem cells. Because I took a guy who was confined to a wheelchair and got him to where he could stay. I did got it. Stand at his bathroom sink for two and a half minutes. It’s incredible. It blew my mind when I saw that. But my uncle, he would go. Actually, we would go for him to the legal marijuana shop and get these candy bars. right and instead of taking a square we would give him a quarter of a square sure he got pain relief slept well slept like a baby and he did this for several years and it was a game changer it opened my eyes because i’m one of these people when i’m kind of straight laced i don’t like the high sure i’m i’m a type a and i have to be in control all the time of every situation But to see what it did for my uncle, it opened my eyes to alternatives that might help him. Is that a good place to start?
SPEAKER 16 :
Is that okay, a quarter of a square? Even circling back to the low-dose ketamine, all of a sudden you take 15 milligrams of a ketamine trochee. Now he can eat the whole square without the anxiety and have more benefits from having four times the amount of just having the quarter.
SPEAKER 03 :
Wow. That’s interesting.
SPEAKER 05 :
Well, anybody who wants the information on getting high, we’ll give you Jeremy’s number afterwards. So you’re listening to Dr. Scott Faulkner, two hours in the can. We’ve got one to go. Please stay tuned. We’ll be right back.
SPEAKER 11 :
Thank you.
